Function and Biology Details
Reactions catalysed:
Cleaves the N-glycosidic bond between the 5'-pyrimidine residue in cyclobutadipyrimidine (in DNA) and the corresponding deoxy-D-ribose residue
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Endonuclease V and DNA (preferred)
PDBe Complex ID:
PDB-CPX-115245 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (3 distinct):
Endonuclease V
Molecule details ›
Chains: A, B
Length: 137 amino acids
Theoretical weight: 15.97 KDa
Source organism: Escherichia virus T4
Expression system: Escherichia coli
UniProt:
Structure domains: T4 endonuclease V
Length: 137 amino acids
Theoretical weight: 15.97 KDa
Source organism: Escherichia virus T4
Expression system: Escherichia coli
UniProt:
- Canonical:
P04418 (Residues: 2-138; Coverage: 99%)
Structure domains: T4 endonuclease V
