› 2fdo

X-ray diffraction
2.4Å resolution

Crystal Structure of the Conserved Protein of Unknown Function AF2331 from Archaeoglobus fulgidus DSM 4304 Reveals a New Type of Alpha/Beta Fold

Released:
DOI: 10.2210/pdb2fdo/pdb
PDB entry 2fdo coloured by chain, front view.
PDB entry 2fdo coloured by chain, side view.
PDB entry 2fdo coloured by chain, top view.
Source organism: Archaeoglobus fulgidus DSM 4304
Primary publication:
The crystal structure of the AF2331 protein from Archaeoglobus fulgidus DSM 4304 forms an unusual interdigitated dimer with a new type of alpha + beta fold.
Wang S, Kirillova O, Chruszcz M, Gront D, Zimmerman MD, Cymborowski MT, Shumilin IA, Skarina T, Gorodichtchenskaia E, Savchenko A, Edwards AM, Minor W
Protein Sci 18 2410-9 (2009)
PMID: 19768810

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127923 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hypothetical protein AF2331 Chains: A, B
Molecule details ›
Chains: A, B
Length: 94 amino acids
Theoretical weight: 10.91 KDa
Source organism: Archaeoglobus fulgidus DSM 4304
Expression system: Escherichia coli
UniProt:
  • Canonical: O27953 (Residues: 1-92; Coverage: 100%)
Gene name: AF_2331
Sequence domains: AF2331-like protein
Structure domains: AF2331-like

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 8 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 45.205Å b: 48.873Å c: 86.693Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.199 0.253
Expression system: Escherichia coli

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Citations

4 citation in other articles

Free Energy Calculations by the Molecular Mechanics Poisson-Boltzmann Surface Area Method.
Homeyer et al. (2012)
3 more

2 mentions without citation

A supersecondary structure library and search algorithm for modeling loops in protein structures.
Fernandez-Fuentes et al. (2006)
1 more