› 2fg9

X-ray diffraction
2.2Å resolution

CRYSTAL STRUCTURE OF A PUTATIVE 5-NITROIMIDAZOLE ANTIBIOTIC RESISTANCE PROTEIN (BT_3078) FROM BACTEROIDES THETAIOTAOMICRON VPI-5482 AT 2.20 A RESOLUTION

Released:
DOI: 10.2210/pdb2fg9/pdb
PDB entry 2fg9 coloured by chain, front view.
PDB entry 2fg9 coloured by chain, side view.
PDB entry 2fg9 coloured by chain, top view.
Source organism: Bacteroides thetaiotaomicron VPI-5482
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183657 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
5-nitroimidazole antibiotic resistance protein Chain: A
Molecule details ›
Chain: A
Length: 178 amino acids
Theoretical weight: 21.01 KDa
Source organism: Bacteroides thetaiotaomicron VPI-5482
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8A377 (Residues: 1-159; Coverage: 100%)
Gene name: BT_3078
Sequence domains: Pyridoxamine 5'-phosphate oxidase
Structure domains: Electron Transport, Fmn-binding Protein; Chain A

Ligands and Environments

3 bound ligands:
Ligand NI 1 x NI
Ligand FAD 1 x FAD
Ligand EDO 1 x EDO
1 modified residue:
Ligand MSE 9 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: I432
Unit cell:
a: 134Å b: 134Å c: 134Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.223 0.245
Expression system: Escherichia coli

Quick links