Function and Biology Details
Reaction catalysed:
An acyl-[acyl-carrier protein] + NAD(+) = a trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assemblies composition:
Assembly name:
PDBe Complex ID:
PDB-CPX-141283 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Molecule details ›
Chains: A, B
Length: 262 amino acids
Theoretical weight: 27.89 KDa
Source organism: Escherichia coli str. K-12 substr. W3110
Expression system: Escherichia coli
UniProt:
Sequence domains: Enoyl-(Acyl carrier protein) reductase
Structure domains: NAD(P)-binding Rossmann-like Domain
Length: 262 amino acids
Theoretical weight: 27.89 KDa
Source organism: Escherichia coli str. K-12 substr. W3110
Expression system: Escherichia coli
UniProt:
- Canonical:
P0AEK4 (Residues: 1-262; Coverage: 100%)
Sequence domains: Enoyl-(Acyl carrier protein) reductase
Structure domains: NAD(P)-binding Rossmann-like Domain
Acyl carrier protein
Molecule details ›
Chain: C
Length: 78 amino acids
Theoretical weight: 8.65 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains: Phosphopantetheine attachment site
Structure domains: ACP-like
Length: 78 amino acids
Theoretical weight: 8.65 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical: P0A6A8 (Residues: 1-78; Coverage: 100%)
Sequence domains: Phosphopantetheine attachment site
Structure domains: ACP-like
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X26C
Spacegroup:
P6522
Expression system: Escherichia coli
