› 2fic

X-ray diffraction
1.99Å resolution

The crystal structure of the BAR domain from human Bin1/Amphiphysin II and its implications for molecular recognition

Released:
DOI: 10.2210/pdb2fic/pdb
PDB entry 2fic coloured by chain, front view.
PDB entry 2fic coloured by chain, side view.
PDB entry 2fic coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The crystal structure of the BAR domain from human Bin1/amphiphysin II and its implications for molecular recognition.
Casal E, Federici L, Zhang W, Fernandez-Recio J, Priego EM, Miguel RN, DuHadaway JB, Prendergast GC, Luisi BF, Laue ED
Biochemistry 45 12917-28 (2006)
PMID: 17059209

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126320 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myc box-dependent-interacting protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 251 amino acids
Theoretical weight: 28.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O00499 (Residues: 1-272; Coverage: 41%)
Gene names: AMPHL, BIN1
Sequence domains: BAR domain
Structure domains: Arfaptin homology (AH) domain/BAR domain

Ligands and Environments

1 bound ligand:
Ligand XE 2 x XE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P21
Unit cell:
a: 69.922Å b: 59.086Å c: 75.009Å
α: 90° β: 117.53° γ: 90°
R-values:
R R work R free
0.311 0.23 0.28
Expression system: Escherichia coli BL21(DE3)

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Citations

14 review citations

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Gay et al. (2014)
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15 mentions without citation

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Xu et al. (2021)
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