› 2fji

X-ray diffraction
2.4Å resolution

Crystal structure of the C-terminal domain of the exocyst subunit Sec6p

Released:
DOI: 10.2210/pdb2fji/pdb
PDB entry 2fji coloured by chain, front view.
PDB entry 2fji coloured by chain, side view.
PDB entry 2fji coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
The structure of the exocyst subunit Sec6p defines a conserved architecture with diverse roles.
Sivaram MV, Furgason ML, Brewer DN, Munson M
Nat Struct Mol Biol 13 555-6 (2006)
PMID: 16699513

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152470 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Exocyst complex component SEC6 Chains: 1, 2
Molecule details ›
Chains: 1, 2
Length: 399 amino acids
Theoretical weight: 46.25 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P32844 (Residues: 411-805; Coverage: 49%)
Gene names: SEC6, YIL068C
Sequence domains: Exocyst complex component Sec6
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A, NSLS BEAMLINE X25
Spacegroup: P21
Unit cell:
a: 108.295Å b: 63.301Å c: 151.468Å
α: 90° β: 103.89° γ: 90°
R-values:
R R work R free
0.249 0.249 0.284
Expression system: Escherichia coli

Quick links

Citations

22 review citations

Role of Rab GTPases in membrane traffic and cell physiology.
Hutagalung et al. (2011)
21 more

19 mentions without citation

Exposing the Elusive Exocyst Structure.
Lepore et al. (2018)
18 more