› 2fkg

X-ray diffraction
2.4Å resolution

The Crystal Structure of Engineered OspA

Released:
DOI: 10.2210/pdb2fkg/pdb
PDB entry 2fkg coloured by chain, front view.
PDB entry 2fkg coloured by chain, side view.
PDB entry 2fkg coloured by chain, top view.
Source organism: Borreliella burgdorferi
Primary publication:
Atomic structures of peptide self-assembly mimics.
Makabe K, McElheny D, Tereshko V, Hilyard A, Gawlak G, Yan S, Koide A, Koide S
Proc Natl Acad Sci U S A 103 17753-8 (2006)
PMID: 17093048

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143538 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Outer surface protein A Chain: A
Molecule details ›
Chain: A
Length: 320 amino acids
Theoretical weight: 34.94 KDa
Source organism: Borreliella burgdorferi
Expression system: Escherichia coli
UniProt:
  • Canonical: P0CL66 (Residues: 27-131, 132-273; Coverage: 96%)
Gene names: BB_A15, ospA
Sequence domains: Borrelia lipoprotein
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: C2
Unit cell:
a: 99.447Å b: 76.894Å c: 51.941Å
α: 90° β: 120° γ: 90°
R-values:
R R work R free
0.22 0.219 0.255
Expression system: Escherichia coli

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Citations

4 review citations

Molecular mechanism of Thioflavin-T binding to amyloid fibrils.
Biancalana et al. (2010)
3 more

6 mentions without citation

Atomic structures of peptide self-assembly mimics.
Makabe et al. (2006)
5 more