› 2fl7

X-ray diffraction
1.85Å resolution

S. cerevisiae Sir3 BAH domain

Released:
DOI: 10.2210/pdb2fl7/pdb
PDB entry 2fl7 coloured by chain, front view.
PDB entry 2fl7 coloured by chain, side view.
PDB entry 2fl7 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structure of the Sir3 protein bromo adjacent homology (BAH) domain from S. cerevisiae at 1.95 A resolution.
Hou Z, Danzer JR, Fox CA, Keck JL
Protein Sci 15 1182-6 (2006)
PMID: 16641491

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139138 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regulatory protein SIR3 Chain: A
Molecule details ›
Chain: A
Length: 232 amino acids
Theoretical weight: 27.5 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P06701 (Residues: 1-229; Coverage: 23%)
Gene names: CMT1, L9753.10, MAR2, SIR3, STE8, YLR442C
Sequence domains: BAH domain
Structure domains: SH3 type barrels.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS FR591
Spacegroup: C2
Unit cell:
a: 94.633Å b: 44.145Å c: 53.723Å
α: 90° β: 96.94° γ: 90°
R-values:
R R work R free
0.2 0.199 0.232
Expression system: Escherichia coli

Quick links

Citations

3 review citations

The role of the nucleosome acidic patch in modulating higher order chromatin structure.
Kalashnikova et al. (2013)
2 more

6 mentions without citation

Polybromo-1: the chromatin targeting subunit of the PBAF complex.
Thompson M. (2009)
5 more