› 2fr9

Solution NMR

NMR structure of the alpha-conotoxin GI (SER12)-benzoylphenylalanine derivative

Released:
DOI: 10.2210/pdb2fr9/pdb
PDB entry 2fr9 coloured by chain, ensemble of 21 models, front view.
PDB entry 2fr9 coloured by chain, ensemble of 21 models, side view.
PDB entry 2fr9 coloured by chain, ensemble of 21 models, top view.
Source organism: Conus geographus
Primary publication:
alpha-Conotoxin GI benzoylphenylalanine derivatives. (1)H-NMR structures and photoaffinity labeling of the Torpedo californica nicotinic acetylcholine receptor.
Kasheverov IE, Chiara DC, Zhmak MN, Maslennikov IV, Pashkov VS, Arseniev AS, Utkin YN, Cohen JB, Tsetlin VI
FEBS J 273 1373-88 (2006)
PMID: 16689926

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162704 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-conotoxin GI Chain: A
Molecule details ›
Chain: A
Length: 13 amino acids
Theoretical weight: 1.61 KDa
Source organism: Conus geographus
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand PBF 1 x PBF

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

5 review citations

Polypeptide and peptide toxins, magnifying lenses for binding sites in nicotinic acetylcholine receptors.
Tsetlin et al. (2009)
4 more

3 mentions without citation

Discovery, synthesis, and structure-activity relationships of conotoxins.
Akondi et al. (2014)
2 more