› 2ftb

X-ray diffraction
2Å resolution

Crystal structure of axolotl (Ambystoma mexicanum) liver bile acid-binding protein bound to oleic acid

Released:
DOI: 10.2210/pdb2ftb/pdb
PDB entry 2ftb coloured by chain, front view.
PDB entry 2ftb coloured by chain, side view.
PDB entry 2ftb coloured by chain, top view.
Source organism: Ambystoma mexicanum
Primary publication:
Crystal structure of axolotl (Ambystoma mexicanum) liver bile acid-binding protein bound to cholic and oleic acid.
Capaldi S, Guariento M, Perduca M, Di Pietro SM, Santomé JA, Monaco HL
Proteins 64 79-88 (2006)
PMID: 16555310

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160514 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein 2, liver Chain: A
Molecule details ›
Chain: A
Length: 125 amino acids
Theoretical weight: 13.76 KDa
Source organism: Ambystoma mexicanum
UniProt:
  • Canonical: P81400 (Residues: 2-126; Coverage: 99%)
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand OLA 1 x OLA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P43212
Unit cell:
a: 66.434Å b: 66.434Å c: 61.724Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.215 0.262

Quick links

Citations

1 review citation

Review: the liver bile acid-binding proteins.
Monaco HL. (2009)
5 other articles

3 mentions without citation

Molecular dynamic simulations reveal the structural determinants of Fatty Acid binding to oxy-myoglobin.
Chintapalli et al. (2015)
2 more