› 2fvu

X-ray diffraction
2Å resolution

Structure of the yeast Sir3 BAH domain

Released:
DOI: 10.2210/pdb2fvu/pdb
PDB entry 2fvu coloured by chain, front view.
PDB entry 2fvu coloured by chain, side view.
PDB entry 2fvu coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structure and function of the Saccharomyces cerevisiae Sir3 BAH domain.
Connelly JJ, Yuan P, Hsu HC, Li Z, Xu RM, Sternglanz R
Mol Cell Biol 26 3256-65 (2006)
PMID: 16581798

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139140 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regulatory protein SIR3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 222 amino acids
Theoretical weight: 26.41 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P06701 (Residues: 1-219; Coverage: 22%)
Gene names: CMT1, L9753.10, MAR2, SIR3, STE8, YLR442C
Sequence domains: BAH domain
Structure domains: SH3 type barrels.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X26C
Spacegroup: P63
Unit cell:
a: 130.39Å b: 130.39Å c: 65.59Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.28 0.28 0.308
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

11 review citations

Nucleosome structure and function.
McGinty et al. (2015)
10 more

2 mentions without citation

Sir3-nucleosome interactions in spreading of silent chromatin in Saccharomyces cerevisiae.
Buchberger et al. (2008)
1 more