› 2fxa

X-ray diffraction
2.4Å resolution

Structure of the Protease Production Regulatory Protein hpr from Bacillus subtilis.

Released:
DOI: 10.2210/pdb2fxa/pdb
PDB entry 2fxa coloured by chain, front view.
PDB entry 2fxa coloured by chain, side view.
PDB entry 2fxa coloured by chain, top view.
Source organism: Bacillus subtilis
Entry authors: Cuff ME, Skarina T, Edwards A, Savchenko A, Joachimiak A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo dimer
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145644 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA-binding transcriptional repressor ScoC Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 207 amino acids
Theoretical weight: 24.41 KDa
Source organism: Bacillus subtilis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P11065 (Residues: 1-203; Coverage: 100%)
Gene names: BSU09990, catA, hpr, scoC
Sequence domains: MarR family
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

4 bound ligands:
Ligand EDO 14 x EDO
Ligand 1PE 2 x 1PE
Ligand P6G 1 x P6G
Ligand PGE 1 x PGE
1 modified residue:
Ligand MSE 28 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 52.272Å b: 79.909Å c: 131.239Å
α: 90° β: 100.18° γ: 90°
R-values:
R R work R free
0.209 0.208 0.234
Expression system: Escherichia coli BL21(DE3)

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