› 2fxu

X-ray diffraction
1.35Å resolution

X-ray Structure of Bistramide A- Actin Complex at 1.35 A resolution.

Released:
DOI: 10.2210/pdb2fxu/pdb
PDB entry 2fxu coloured by chain, front view.
PDB entry 2fxu coloured by chain, side view.
PDB entry 2fxu coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
Structure of bistramide A-actin complex at a 1.35 angstroms resolution.
Rizvi SA, Tereshko V, Kossiakoff AA, Kozmin SA
J Am Chem Soc 128 3882-3 (2006)
PMID: 16551075

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159302 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Actin, alpha skeletal muscle Chain: A
Molecule details ›
Chain: A
Length: 375 amino acids
Theoretical weight: 41.88 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P68135 (Residues: 3-377; Coverage: 100%)
Gene names: ACTA, ACTA1
Sequence domains: Actin
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand CA 4 x CA
Ligand ATP 1 x ATP
Ligand BID 1 x BID
1 modified residue:
Ligand HIC 1 x HIC

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: C2
Unit cell:
a: 60.125Å b: 56.513Å c: 101.652Å
α: 90° β: 94.56° γ: 90°
R-values:
R R work R free
0.176 0.174 0.201

Quick links

Citations

6 review citations

Marine natural products.
Blunt et al. (2008)
5 more

13 mentions without citation

Actin structure and function.
Dominguez et al. (2011)
12 more