› 2fy8

X-ray diffraction
2.79Å resolution

Crystal structure of MthK rck domain in its ligand-free gating-ring form

Released:
DOI: 10.2210/pdb2fy8/pdb
PDB entry 2fy8 coloured by chain, front view.
PDB entry 2fy8 coloured by chain, side view.
PDB entry 2fy8 coloured by chain, top view.
Source organism: Methanothermobacter thermautotrophicus
Primary publication:
Crystal structures of a ligand-free MthK gating ring: insights into the ligand gating mechanism of K+ channels.
Ye S, Li Y, Chen L, Jiang Y
Cell 126 1161-73 (2006)
PMID: 16990139

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127900 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium-gated potassium channel MthK Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 230 amino acids
Theoretical weight: 25.45 KDa
Source organism: Methanothermobacter thermautotrophicus
Expression system: Escherichia coli
UniProt:
  • Canonical: O27564 (Residues: 107-336; Coverage: 69%)
Gene names: MTH_1520, mthK
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2221
Unit cell:
a: 174.141Å b: 180.965Å c: 252.748Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.212 0.254
Expression system: Escherichia coli

Quick links

Citations

15 review citations

BK channel activation: structural and functional insights.
Lee et al. (2010)
14 more

14 mentions without citation

Structure of potassium channels.
Kuang et al. (2015)
13 more