› 2g34

X-ray diffraction
5.05Å resolution

Human hepatitis B virus T=4 capsid strain adyw complexed with assembly effector HAP1

Released:
DOI: 10.2210/pdb2g34/pdb
PDB entry 2g34 coloured by chain, front view.
PDB entry 2g34 coloured by chain, side view.
PDB entry 2g34 coloured by chain, top view.
Source organism: Hepatitis B virus subtype adyw
Primary publication:
Global structural changes in hepatitis B virus capsids induced by the assembly effector HAP1.
Bourne CR, Finn MG, Zlotnick A
J Virol 80 11055-61 (2006)
PMID: 16943288

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo 240-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136619 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 150 amino acids
Theoretical weight: 16.79 KDa
Source organism: Hepatitis B virus subtype adyw
Expression system: Escherichia coli
UniProt:
  • Canonical: P03147 (Residues: 1-149; Coverage: 81%)
Gene name: C
Sequence domains: Hepatitis core antigen

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-D
Spacegroup: C2
Unit cell:
a: 528.53Å b: 366.47Å c: 540.07Å
α: 90° β: 104.83° γ: 90°
R-values:
R R work R free
0.365 0.365 not available
Expression system: Escherichia coli

Quick links

Citations

17 review citations

Core protein: A pleiotropic keystone in the HBV lifecycle.
Zlotnick et al. (2015)
16 more

12 mentions without citation

Virus assembly, allostery and antivirals.
Zlotnick et al. (2011)
11 more