› 2g3y

X-ray diffraction
2.4Å resolution

Crystal structure of the human small GTPase GEM

Released:
DOI: 10.2210/pdb2g3y/pdb
PDB entry 2g3y coloured by chain, front view.
PDB entry 2g3y coloured by chain, side view.
PDB entry 2g3y coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Ugochukwu E, Soundararajan M, Elkins J, Gileadi C, Schoch G, Sobott F, Fedorov O, Bray J, Pantic N, Berridge G, Burgess N, Lee WH, Turnbull A, Sundstrom M, Arrowsmith C, Weigelt J, Edwards A, von Delft F, Doyle D, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157156 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GTP-binding protein GEM Chain: A
Molecule details ›
Chain: A
Length: 211 amino acids
Theoretical weight: 23.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P55040 (Residues: 62-249; Coverage: 64%)
Gene names: GEM, KIR
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

1 bound ligand:
Ligand GDP 1 x GDP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P43212
Unit cell:
a: 51.242Å b: 51.242Å c: 173.873Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.218 0.269
Expression system: Escherichia coli

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