› 2g85

X-ray diffraction
2.22Å resolution

Crystal structure of chorismate synthase from Mycobacterium tuberculosis at 2.22 angstrons of resolution

Released:
DOI: 10.2210/pdb2g85/pdb
Model geometry
Fit model/data
PDB entry 2g85 coloured by chain, front view.
PDB entry 2g85 coloured by chain, side view.
PDB entry 2g85 coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Entry authors: Dias MVB, dos Santos BB, Ely F, Basso LA, Santos DS, de Azevedo Jr WF

Function and Biology Details

Reaction catalysed: 
5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162024 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chorismate synthase Chain: A
Molecule details ›
Chain: A
Length: 401 amino acids
Theoretical weight: 41.84 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WPY1 (Residues: 1-401; Coverage: 100%)
Gene names: MTCY159.16, Rv2540c, aroC, aroF
Sequence domains: Chorismate synthase
Structure domains: Chorismate synthase AroC

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: LNLS BEAMLINE D03B-MX1
Spacegroup: P6422
Unit cell:
a: 130.288Å b: 130.288Å c: 157.95Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.175 0.173 0.214
Expression system: Escherichia coli

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