› 2g9c

X-ray diffraction
1.7Å resolution

Modified pyrimidines Specifically bind the purine riboswitch

Released:
DOI: 10.2210/pdb2g9c/pdb
PDB entry 2g9c coloured by chain, front view.
PDB entry 2g9c coloured by chain, side view.
PDB entry 2g9c coloured by chain, top view.
Source organism: Bacillus subtilis
Primary publication:
Modified pyrimidines specifically bind the purine riboswitch.
Gilbert SD, Mediatore SJ, Batey RT
J Am Chem Soc 128 14214-5 (2006)
PMID: 17076468

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195852 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
guanine riboswitch Chain: A
Molecule details ›
Chain: A
Length: 67 nucleotides
Theoretical weight: 21.51 KDa
Source organism: Bacillus subtilis
Expression system: Not provided
Sequence domains: Purine riboswitch

Ligands and Environments

3 bound ligands:
Ligand ACT 1 x ACT
Ligand NCO 12 x NCO
Ligand 3AY 1 x 3AY
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: C2
Unit cell:
a: 131.99Å b: 35.1Å c: 41.8Å
α: 90° β: 90.43° γ: 90°
R-values:
R R work R free
0.233 0.195 0.242
Expression system: Not provided

Quick links

Citations

15 review citations

RNA Structural Dynamics As Captured by Molecular Simulations: A Comprehensive Overview.
Šponer et al. (2018)
14 more

6 mentions without citation

Using RNA Sequence and Structure for the Prediction of Riboswitch Aptamer: A Comprehensive Review of Available Software and Tools.
Antunes et al. (2017)
5 more