› 2g9p

Solution NMR

NMR structure of a novel antimicrobial peptide, latarcin 2a, from spider (Lachesana tarabaevi) venom

Released:
DOI: 10.2210/pdb2g9p/pdb
PDB entry 2g9p coloured by chain, ensemble of 20 models, front view.
PDB entry 2g9p coloured by chain, ensemble of 20 models, side view.
PDB entry 2g9p coloured by chain, ensemble of 20 models, top view.
Source organism: Lachesana tarabaevi
Primary publication:
Spatial structure and activity mechanism of a novel spider antimicrobial peptide.
Dubovskii PV, Volynsky PE, Polyansky AA, Chupin VV, Efremov RG, Arseniev AS
Biochemistry 45 10759-67 (2006)
PMID: 16939228

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172820 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
M-zodatoxin-Lt2a Chain: A
Molecule details ›
Chain: A
Length: 26 amino acids
Theoretical weight: 2.91 KDa
Source organism: Lachesana tarabaevi
Expression system: Not provided
UniProt:
  • Canonical: Q1ELU1 (Residues: 59-84; Coverage: 42%)
Sequence domains: Latarcin precursor

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics followed by refinement in implicit membrane model (water/octanol/water slab)
Expression system: Not provided

Quick links

Citations

4 review citations

Molecular diversity of spider venom.
Vassilevski et al. (2009)
3 more

3 mentions without citation

Spider venom peptides as potential drug candidates due to their anticancer and antinociceptive activities.
Wu et al. (2019)
2 more