› 2gfp

X-ray diffraction
3.5Å resolution

Structure of the Multidrug Transporter EmrD from Escherichia coli

Released:
DOI: 10.2210/pdb2gfp/pdb
PDB entry 2gfp coloured by chain, front view.
PDB entry 2gfp coloured by chain, side view.
PDB entry 2gfp coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Structure of the multidrug transporter EmrD from Escherichia coli.
Yin Y, He X, Szewczyk P, Nguyen T, Chang G
Science 312 741-4 (2006)
PMID: 16675700

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152014 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Multidrug resistance protein D Chains: A, B
Molecule details ›
Chains: A, B
Length: 375 amino acids
Theoretical weight: 40.01 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P31442 (Residues: 9-383; Coverage: 95%)
Gene names: JW5634, b3673, emrD, yicQ
Sequence domains: Fungal trichothecene efflux pump (TRI12)
Structure domains: Multidrug resistance protein D

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: C2
Unit cell:
a: 137.5Å b: 124.5Å c: 109.4Å
α: 90° β: 110.2° γ: 90°
R-values:
R R work R free
0.28 0.27 0.35
Expression system: Escherichia coli

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Citations

64 review citations

Multidrug resistance in bacteria.
Nikaido H. (2009)
63 more

59 mentions without citation

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