› 2ggr

Solution NMR

Solution structure of the C-terminal SH3 domain of c-CrkII

Released:
DOI: 10.2210/pdb2ggr/pdb
PDB entry 2ggr coloured by chain, ensemble of 20 models, front view.
PDB entry 2ggr coloured by chain, ensemble of 20 models, side view.
PDB entry 2ggr coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Primary publication:
Solution structure and folding characteristics of the C-terminal SH3 domain of c-Crk-II.
Muralidharan V, Dutta K, Cho J, Vila-Perello M, Raleigh DP, Cowburn D, Muir TW
Biochemistry 45 8874-84 (2006)
PMID: 16846230

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179108 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adapter molecule crk Chain: A
Molecule details ›
Chain: A
Length: 76 amino acids
Theoretical weight: 8.53 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q64010 (Residues: 230-304; Coverage: 25%)
Gene names: Crk, Crko
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

9 review citations

SH3 domains: modules of protein-protein interactions.
Kurochkina et al. (2013)
8 more

2 mentions without citation

Proline cis-trans isomerization controls autoinhibition of a signaling protein.
Sarkar et al. (2007)
1 more