› 2ggt

X-ray diffraction
2.4Å resolution

Crystal structure of human SCO1 complexed with nickel.

Released:
DOI: 10.2210/pdb2ggt/pdb
PDB entry 2ggt coloured by chain, front view.
PDB entry 2ggt coloured by chain, side view.
PDB entry 2ggt coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
A hint for the function of human Sco1 from different structures.
Banci L, Bertini I, Calderone V, Ciofi-Baffoni S, Mangani S, Martinelli M, Palumaa P, Wang S
Proc Natl Acad Sci U S A 103 8595-600 (2006)
PMID: 16735468

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131151 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein SCO1 homolog, mitochondrial Chains: A, B
Molecule details ›
Chains: A, B
Length: 164 amino acids
Theoretical weight: 18.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75880 (Residues: 135-298; Coverage: 55%)
Gene names: SCO1, SCOD1
Sequence domains: SCO1/SenC
Structure domains: Glutaredoxin

Ligands and Environments

2 bound ligands:
Ligand NI 2 x NI
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P212121
Unit cell:
a: 51.461Å b: 52.444Å c: 136.411Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.226 0.217 0.318
Expression system: Escherichia coli

Quick links

Citations

19 review citations

Copper metallochaperones.
Robinson et al. (2010)
18 more

2 mentions without citation

A hint for the function of human Sco1 from different structures.
Banci et al. (2006)
1 more