› 2gmo

Solution NMR

NMR-structure of an independently folded C-terminal domain of influenza polymerase subunit PB2

Released:
DOI: 10.2210/pdb2gmo/pdb
PDB entry 2gmo coloured by chain, ensemble of 10 models, front view.
PDB entry 2gmo coloured by chain, ensemble of 10 models, side view.
PDB entry 2gmo coloured by chain, ensemble of 10 models, top view.
Source organism: Influenza A virus (A/Victoria/3/1975(H3N2))
Primary publication:
Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit.
Tarendeau F, Boudet J, Guilligay D, Mas PJ, Bougault CM, Boulo S, Baudin F, Ruigrok RW, Daigle N, Ellenberg J, Cusack S, Simorre JP, Hart DJ
Nat Struct Mol Biol 14 229-33 (2007)
PMID: 17310249

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151984 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polymerase basic protein 2 Chain: A
Molecule details ›
Chain: A
Length: 83 amino acids
Theoretical weight: 8.99 KDa
Source organism: Influenza A virus (A/Victoria/3/1975(H3N2))
Expression system: Escherichia coli
UniProt:
  • Canonical: P31345 (Residues: 678-759; Coverage: 11%)
Gene name: PB2
Sequence domains: Influenza RNA polymerase PB2 C-terminal domain
Structure domains: Polymerase Basic Protein 2, C-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

47 review citations

Influenza virus evolution, host adaptation, and pandemic formation.
Taubenberger et al. (2010)
46 more

4 mentions without citation

Mapping the phosphoproteome of influenza A and B viruses by mass spectrometry.
Hutchinson et al. (2012)
3 more