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Solution NMR

Solution structure of Murine p22HBP

Released:
DOI: 10.2210/pdb2gov/pdb
PDB entry 2gov coloured by chain, ensemble of 20 models, front view.
PDB entry 2gov coloured by chain, ensemble of 20 models, side view.
PDB entry 2gov coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Primary publication:
The first structure from the SOUL/HBP family of heme-binding proteins, murine P22HBP.
Dias JS, Macedo AL, Ferreira GC, Peterson FC, Volkman BF, Goodfellow BJ
J Biol Chem 281 31553-61 (2006)
PMID: 16905545

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193102 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heme-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 195 amino acids
Theoretical weight: 21.78 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9R257 (Residues: 7-190; Coverage: 97%)
Gene names: Hbp, Hebp1
Sequence domains: SOUL heme-binding protein
Structure domains: Regulatory factor, effector binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: AUTOMATED METHODS WERE USED FOR BACKBONE CHEMICAL SHIFT ASSIGNMENT AND ITERATIVE NOE REFINEMENT. FINAL STRUCTURES WERE OBTAINED BY MOLECULAR DYNAMICS IN EXPLICIT SOLVENT
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

Mechanisms of mitochondrial dysfunction and energy deficiency in Alzheimer's disease.
Atamna et al. (2007)
5 more

1 mention without citation

Preliminary structural characterization of human SOUL, a haem-binding protein.
Freire et al. (2009)