› 2gsr

X-ray diffraction
2.11Å resolution

Structure of porcine class pi glutathione s-transferase

Released:
DOI: 10.2210/pdb2gsr/pdb
PDB entry 2gsr coloured by chain, front view.
PDB entry 2gsr coloured by chain, side view.
PDB entry 2gsr coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
Refined crystal structure of porcine class Pi glutathione S-transferase (pGST P1-1) at 2.1 A resolution.
Dirr H, Reinemer P, Huber R
J Mol Biol 243 72-92 (1994)
PMID: 7932743

Function and Biology Details

Reaction catalysed: 
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160333 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase P Chains: A, B
Molecule details ›
Chains: A, B
Length: 207 amino acids
Theoretical weight: 23.54 KDa
Source organism: Sus scrofa
Expression system: Not provided
UniProt:
  • Canonical: P80031 (Residues: 1-206; Coverage: 100%)
Gene name: GSTP1
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand GTS 2 x GTS
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 101.25Å b: 82.53Å c: 54.28Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.165 0.165 not available
Expression system: Not provided

Quick links

Citations

5 review citations

Glutathione transferases in the genomics era: new insights and perspectives.
Frova C. (2006)
4 more

8 mentions without citation

The molecular refractive function of lens γ-Crystallins.
Zhao et al. (2011)
7 more