› 2gu0

X-ray diffraction
2.8Å resolution

Crystal Structure of Human Rotavirus NSP2 (Group C / Bristol Strain)

Released:
DOI: 10.2210/pdb2gu0/pdb
PDB entry 2gu0 coloured by chain, front view.
PDB entry 2gu0 coloured by chain, side view.
PDB entry 2gu0 coloured by chain, top view.
Source organism: Human rotavirus C
Primary publication:
Structure-function analysis of rotavirus NSP2 octamer by using a novel complementation system.
Taraporewala ZF, Jiang X, Vasquez-Del Carpio R, Jayaram H, Prasad BV, Patton JT
J. Virol. 80 7984-94 (2006)
PMID: 16873255

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192954 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Non-structural protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 312 amino acids
Theoretical weight: 35.96 KDa
Source organism: Human rotavirus C
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9PY93 (Residues: 1-312; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: I4
Unit cell:
a: 134.181Å b: 134.181Å c: 112.294Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.238 0.231 0.283
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Reassortment in segmented RNA viruses: mechanisms and outcomes.
McDonald et al. (2016)
3 more