› 2gzw

X-ray diffraction
2.21Å resolution

Crystal structure of the E.coli CRP-cAMP complex

Released:
DOI: 10.2210/pdb2gzw/pdb
PDB entry 2gzw coloured by chain, front view.
PDB entry 2gzw coloured by chain, side view.
PDB entry 2gzw coloured by chain, top view.
Source organism: Escherichia coli
Entry authors: Kumarevel TS, Tanaka T, Shinkai A, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142283 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA-binding transcriptional dual regulator CRP Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 209 amino acids
Theoretical weight: 23.54 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0ACJ8 (Residues: 2-210; Coverage: 100%)
Gene names: JW5702, b3357, cap, crp, csm
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CMP 8 x CMP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: P1
Unit cell:
a: 45.37Å b: 57.15Å c: 90.74Å
α: 91.25° β: 101.95° γ: 103.7°
R-values:
R R work R free
0.224 0.224 0.278
Expression system: Escherichia coli

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