› 2h0u

X-ray diffraction
1.9Å resolution

Crystal structure of NAD(P)H-flavin oxidoreductase from Helicobacter pylori

Released:
DOI: 10.2210/pdb2h0u/pdb
PDB entry 2h0u coloured by chain, front view.
PDB entry 2h0u coloured by chain, side view.
PDB entry 2h0u coloured by chain, top view.
Source organism: Helicobacter pylori
Entry authors: Chang C, Xu X, Zheng H, Savchenko A, Edwards A, Joachimiak A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181362 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nitroreductase domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 217 amino acids
Theoretical weight: 25.89 KDa
Source organism: Helicobacter pylori
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7BGI8 (Residues: 1-217; Coverage: 100%)
Gene names: C2R45_03525, C2S01_06315, C2S07_02150, D8X81_03425, DD767_02880, DDP35_03535, EC527_03545, F7198_05755, frxA
Sequence domains: Nitroreductase family
Structure domains: NADH Oxidase

Ligands and Environments

1 bound ligand:
Ligand FMN 1 x FMN
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2221
Unit cell:
a: 54.035Å b: 87.178Å c: 94.979Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.178 0.221
Expression system: Escherichia coli

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