› 2h5f

X-ray diffraction
1.9Å resolution

Denmotoxin: A the three-finger toxin from colubrid snake Boiga dendrophila with bird-specific activity

Released:
DOI: 10.2210/pdb2h5f/pdb
PDB entry 2h5f coloured by chain, front view.
PDB entry 2h5f coloured by chain, side view.
PDB entry 2h5f coloured by chain, top view.
Source organism: Boiga dendrophila
Primary publication:
Denmotoxin, a three-finger toxin from the colubrid snake Boiga dendrophila (Mangrove Catsnake) with bird-specific activity.
Pawlak J, Mackessy SP, Fry BG, Bhatia M, Mourier G, Fruchart-Gaillard C, Servent D, Ménez R, Stura E, Ménez A, Kini RM
J Biol Chem 281 29030-41 (2006)
PMID: 16864572

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170430 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Denmotoxin Chains: A, B
Molecule details ›
Chains: A, B
Length: 77 amino acids
Theoretical weight: 8.55 KDa
Source organism: Boiga dendrophila
UniProt:
  • Canonical: Q06ZW0 (Residues: 35-111; Coverage: 84%)
Structure domains: CD59

Ligands and Environments

3 bound ligands:
Ligand PO4 4 x PO4
Ligand K 2 x K
Ligand NA 2 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2
Unit cell:
a: 98.91Å b: 34.038Å c: 54.377Å
α: 90° β: 118.36° γ: 90°
R-values:
R R work R free
0.204 0.202 0.238

Quick links

Citations

23 review citations

Complex cocktails: the evolutionary novelty of venoms.
Casewell et al. (2013)
22 more

4 mentions without citation

Studies on sea snake venom.
Tamiya et al. (2011)
3 more