› 2h6c

X-ray diffraction
2.9Å resolution

Crystal structure of reduced CprK in absence of any ligand

Released:
DOI: 10.2210/pdb2h6c/pdb
PDB entry 2h6c coloured by chain, front view.
PDB entry 2h6c coloured by chain, side view.
PDB entry 2h6c coloured by chain, top view.
Source organism: Desulfitobacterium dehalogenans
Primary publication:
CprK crystal structures reveal mechanism for transcriptional control of halorespiration.
Joyce MG, Levy C, Gábor K, Pop SM, Biehl BD, Doukov TI, Ryter JM, Mazon H, Smidt H, van den Heuvel RH, Ragsdale SW, van der Oost J, Leys D
J Biol Chem 281 28318-25 (2006)
PMID: 16803881

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192240 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative transcription regulator Chains: A, B
Molecule details ›
Chains: A, B
Length: 232 amino acids
Theoretical weight: 26.68 KDa
Source organism: Desulfitobacterium dehalogenans
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9LAS2 (Residues: 1-232; Coverage: 100%)
Gene name: cprK
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P21
Unit cell:
a: 72.637Å b: 50.03Å c: 76.415Å
α: 90° β: 105.54° γ: 90°
R-values:
R R work R free
0.235 0.232 0.307
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Thiol-based redox switches and gene regulation.
Antelmann et al. (2011)
3 more

3 mentions without citation

The Landscape of Intertwined Associations in Homooligomeric Proteins.
Wodak et al. (2015)
2 more