Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178913 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SH2B adapter protein 1
Molecule details ›
Chains: A, B, C, D, E, F
Length: 111 amino acids
Theoretical weight: 12.28 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: SH2 domain
Structure domains: SH2 domain
Length: 111 amino acids
Theoretical weight: 12.28 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q91ZM2 (Residues: 519-627; Coverage: 14%)
Sequence domains: SH2 domain
Structure domains: SH2 domain
Tyrosine-protein kinase JAK2
Molecule details ›
Chains: G, H, I, J, K, L
Length: 11 amino acids
Theoretical weight: 1.39 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
Length: 11 amino acids
Theoretical weight: 1.39 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
- Canonical: Q62120 (Residues: 810-820; Coverage: 1%)
