› 2he2

X-ray diffraction
1.5Å resolution

Crystal structure of the 3rd PDZ domain of human discs large homologue 2, DLG2

Released:
DOI: 10.2210/pdb2he2/pdb
PDB entry 2he2 coloured by chain, front view.
PDB entry 2he2 coloured by chain, side view.
PDB entry 2he2 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Elkins JM, Papagrigoriou E, Berridge G, Yang X, Phillips C, Gileadi C, Savitsky P, Doyle DA
Protein Sci 16 683-94 (2007)
PMID: 17384233

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172378 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Disks large homolog 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 102 amino acids
Theoretical weight: 10.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15700 (Residues: 418-513; Coverage: 11%)
Gene name: DLG2
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P212121
Unit cell:
a: 56.155Å b: 56.07Å c: 60.472Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.13 0.127 0.187
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Engineering of recombinant crystallization chaperones.
Koide S. (2009)
5 more

10 mentions without citation

A Review on Cyclodextrins/Estrogens Inclusion Complexes.
Araj et al. (2023)
9 more