› 2hew

X-ray diffraction
1.45Å resolution

The X-ray crystal structure of murine OX40L

Released:
DOI: 10.2210/pdb2hew/pdb
PDB entry 2hew coloured by chain, front view.
PDB entry 2hew coloured by chain, side view.
PDB entry 2hew coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
The crystal structure of the costimulatory OX40-OX40L complex.
Compaan DM, Hymowitz SG
Structure 14 1321-30 (2006)
PMID: 16905106

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155074 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor necrosis factor ligand superfamily member 4 Chain: F
Molecule details ›
Chain: F
Length: 152 amino acids
Theoretical weight: 17.06 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P43488 (Residues: 51-198; Coverage: 75%)
Gene names: Ox40l, Tnfsf4, Txgp1l
Structure domains: Jelly Rolls

Ligands and Environments

2 bound ligands:
Ligand NAG 1 x NAG
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1, ALS BEAMLINE 5.0.2
Spacegroup: P63
Unit cell:
a: 74.149Å b: 74.149Å c: 48.815Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.168 0.165 0.192
Expression system: Spodoptera frugiperda

Quick links

Citations

26 review citations

Control of immunity by the TNFR-related molecule OX40 (CD134).
Croft M. (2010)
25 more

2 mentions without citation

Discordant and chameleon sequences: their distribution and implications for amyloidogenicity.
Gendoo et al. (2011)
1 more