Function and Biology Details
Reaction catalysed:
L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Branched-chain amino acid aminotransferase II
- Aminotransferase, class IV, conserved site
- Branched-chain-amino-acid aminotransferase-like, C-terminal
- Aminotransferase class IV
- Branched-chain aminotransferase
- Aminotransferase-like, PLP-dependent enzymes
- Branched-chain-amino-acid aminotransferase-like, N-terminal
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127454 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Branched-chain-amino-acid aminotransferase, mitochondrial
Molecule details ›
Chains: A, B
Length: 365 amino acids
Theoretical weight: 41.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Amino-transferase class IV
Structure domains:
Length: 365 amino acids
Theoretical weight: 41.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
O15382 (Residues: 28-392; Coverage: 93%)
Sequence domains: Amino-transferase class IV
Structure domains:
Ligands and Environments
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
CHESS BEAMLINE F1
Spacegroup:
P212121
Expression system: Escherichia coli BL21(DE3)
