› 2hn2

X-ray diffraction
3.7Å resolution

Crystal structure of the CorA Mg2+ transporter homologue from T. maritima in complex with divalent cations

Released:
DOI: 10.2210/pdb2hn2/pdb
PDB entry 2hn2 coloured by chain, front view.
PDB entry 2hn2 coloured by chain, side view.
PDB entry 2hn2 coloured by chain, top view.
Source organism: Thermotoga maritima
Primary publication:
A structural basis for Mg2+ homeostasis and the CorA translocation cycle.
Payandeh J, Pai EF
EMBO J 25 3762-73 (2006)
PMID: 16902408

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194571 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cobalt/magnesium transport protein CorA Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 354 amino acids
Theoretical weight: 41.78 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9WZ31 (Residues: 1-351; Coverage: 100%)
Gene names: TM_0561, corA
Sequence domains: CorA-like Mg2+ transporter protein
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CA 13 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X8C
Spacegroup: C2
Unit cell:
a: 214.246Å b: 86.298Å c: 181.527Å
α: 90° β: 112.23° γ: 90°
R-values:
R R work R free
0.295 0.295 0.316
Expression system: Escherichia coli

Quick links

Citations

12 review citations

Bacterial Mg2+ homeostasis, transport, and virulence.
Groisman et al. (2013)
11 more

7 mentions without citation

Advances in imaging of understudied ions in signaling: A focus on magnesium.
Lazarou et al. (2020)
6 more