› 2hn8

Solution NMR

Structural characterization and oligomerization of PB1-F2, a pro-apoptotic influenza A virus protein

Released:
DOI: 10.2210/pdb2hn8/pdb
PDB entry 2hn8 coloured by chain, ensemble of 20 models, front view.
PDB entry 2hn8 coloured by chain, ensemble of 20 models, side view.
PDB entry 2hn8 coloured by chain, ensemble of 20 models, top view.
Source organism: Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Primary publication:
Structural characterization and oligomerization of PB1-F2, a proapoptotic influenza A virus protein.
Bruns K, Studtrucker N, Sharma A, Fossen T, Mitzner D, Eissmann A, Tessmer U, Röder R, Henklein P, Wray V, Schubert U
J Biol Chem 282 353-63 (2007)
PMID: 17052982

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142912 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein PB1-F2 Chain: A
Molecule details ›
Chain: A
Length: 38 amino acids
Theoretical weight: 4.85 KDa
Source organism: Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Expression system: Not provided
UniProt:
  • Canonical: P0C0U1 (Residues: 50-87; Coverage: 44%)
Gene name: PB1
Sequence domains: Influenza A Proapoptotic protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

15 review citations

Viruses as modulators of mitochondrial functions.
Anand et al. (2013)
14 more

6 mentions without citation

The proapoptotic influenza A virus protein PB1-F2 forms a nonselective ion channel.
Henkel et al. (2010)
5 more