Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Error-prone DNA polymerase/DNA polymerase III subunit alpha DnaE/PolC
- DNA polymerase, helix-hairpin-helix motif
- DNA polymerase III alpha subunit finger domain
- Bacterial DNA polymerase III alpha subunit, thumb domain
- Bacterial DNA polymerase III, alpha subunit, NTPase domain
- PHP domain
- Polymerase/histidinol phosphatase, N-terminal
- Polymerase/histidinol phosphatase-like
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
DNA polymerase III subunit alpha (preferred)
PDBe Complex ID:
PDB-CPX-145311 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA polymerase III subunit alpha
Molecule details ›
Chain: A
Length: 910 amino acids
Theoretical weight: 101.76 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 910 amino acids
Theoretical weight: 101.76 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical:
P10443 (Residues: 1-910; Coverage: 78%)
Sequence domains:
- PHP domain
- Bacterial DNA polymerase III alpha NTPase domain
- Bacterial DNA polymerase III alpha subunit finger domain
- Helix-hairpin-helix motif
