› 2hp0

X-ray diffraction
1.5Å resolution

Crystal structure of iminodisuccinate epimerase

Released:
DOI: 10.2210/pdb2hp0/pdb
Model geometry
Fit model/data
PDB entry 2hp0 coloured by chain, front view.
PDB entry 2hp0 coloured by chain, side view.
PDB entry 2hp0 coloured by chain, top view.
Source organism: Agrobacterium tumefaciens
Primary publication:
Three-dimensional structure of iminodisuccinate epimerase defines the fold of the MmgE/PrpD protein family.
Lohkamp B, Bäuerle B, Rieger PG, Schneider G
J Mol Biol 362 555-66 (2006)
PMID: 16934291

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172934 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
IDS-epimerase Chain: A
Molecule details ›
Chain: A
Length: 466 amino acids
Theoretical weight: 50.59 KDa
Source organism: Agrobacterium tumefaciens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q1L4E3 (Residues: 1-446; Coverage: 100%)
Sequence domains:
Structure domains:
IDS-epimerase Chain: B
Molecule details ›
Chain: B
Length: 466 amino acids
Theoretical weight: 50.6 KDa
Source organism: Agrobacterium tumefaciens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q1L4E3 (Residues: 1-446; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand EDO 6 x EDO
Ligand UNX 14 x UNX
Ligand DTU 2 x DTU
2 modified residues:
Ligand MSE 34 x MSE
Ligand CSO 1 x CSO

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P21
Unit cell:
a: 55.602Å b: 104.973Å c: 78.645Å
α: 90° β: 102.51° γ: 90°
R-values:
R R work R free
0.152 0.151 0.174
Expression system: Escherichia coli

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Citations

1 review citation

ACOD1 in immunometabolism and disease.
Wu et al. (2020)
8 other articles

4 mentions without citation

Problems of robustness in Poisson-Boltzmann binding free energies.
Harris et al. (2015)
3 more