Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Error-prone DNA polymerase/DNA polymerase III subunit alpha DnaE/PolC
- DNA polymerase, helix-hairpin-helix motif
- DNA polymerase III alpha subunit finger domain
- Bacterial DNA polymerase III alpha subunit, thumb domain
- Bacterial DNA polymerase III, alpha subunit, NTPase domain
- PHP domain
- Polymerase/histidinol phosphatase, N-terminal
- Polymerase/histidinol phosphatase-like
Structure analysis Details
Assemblies composition:
Assembly name:
DNA polymerase III subunit alpha (preferred)
PDBe Complex ID:
PDB-CPX-195000 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA polymerase III subunit alpha
Molecule details ›
Chain: A
Length: 1220 amino acids
Theoretical weight: 137.58 KDa
Source organism: Thermus aquaticus
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 1220 amino acids
Theoretical weight: 137.58 KDa
Source organism: Thermus aquaticus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9XDH5 (Residues: 1-1220; Coverage: 100%)
Sequence domains:
- PHP domain
- Bacterial DNA polymerase III alpha NTPase domain
- Bacterial DNA polymerase III alpha subunit finger domain
- Helix-hairpin-helix motif
- OB-fold nucleic acid binding domain
