› 2hps

X-ray diffraction
1.72Å resolution

Crystal structure of coelenterazine-binding protein from Renilla Muelleri

Released:
DOI: 10.2210/pdb2hps/pdb
PDB entry 2hps coloured by chain, front view.
PDB entry 2hps coloured by chain, side view.
PDB entry 2hps coloured by chain, top view.
Source organism: Renilla muelleri
Primary publication:
Crystal structure of coelenterazine-binding protein from Renilla muelleri at 1.7 A: why it is not a calcium-regulated photoprotein.
Stepanyuk GA, Liu ZJ, Markova SS, Frank LA, Lee J, Vysotski ES, Wang BC
Photochem Photobiol Sci 7 442-7 (2008)
PMID: 18385886

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111878 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
EF-hand domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 186 amino acids
Theoretical weight: 21.13 KDa
Source organism: Renilla muelleri
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: C9V488 (Residues: 1-186; Coverage: 100%)
Gene name: CBP1
Sequence domains:
Structure domains: EF-hand

Ligands and Environments

2 bound ligands:
Ligand CTZ 1 x CTZ
Ligand GOL 2 x GOL
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P6522
Unit cell:
a: 55.948Å b: 55.948Å c: 292.202Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.199 0.229
Expression system: Escherichia coli BL21

Quick links

Citations

4 review citations

Coelenterazine-dependent luciferases.
Markova et al. (2015)
3 more

8 mentions without citation

Molecular representations in AI-driven drug discovery: a review and practical guide.
David et al. (2020)
7 more