› 2hsr

Solution NMR

13mer duplex DNA containing an abasic site with beta anomer

Released:
DOI: 10.2210/pdb2hsr/pdb
PDB entry 2hsr coloured by chain, ensemble of 10 models, front view.
PDB entry 2hsr coloured by chain, ensemble of 10 models, side view.
PDB entry 2hsr coloured by chain, ensemble of 10 models, top view.
Source organism: synthetic construct
Primary publication:
Nuclear magnetic resonance structural studies and molecular modeling of duplex DNA containing normal and 4'-oxidized abasic sites.
Chen J, Dupradeau FY, Case DA, Turner CJ, Stubbe J
Biochemistry 46 3096-107 (2007)
PMID: 17323932

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115364 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
5'-D(*CP*CP*AP*AP*AP*GP*(AAB)P*AP*CP*CP*GP*GP*G)-3' Chain: A
Molecule details ›
Chain: A
Length: 13 nucleotides
Theoretical weight: 3.88 KDa
Source organism: synthetic construct
Expression system: Not provided
5'-D(*CP*CP*CP*GP*GP*TP*AP*CP*TP*TP*TP*GP*G)-3' Chain: B
Molecule details ›
Chain: B
Length: 13 nucleotides
Theoretical weight: 3.96 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing molecular dynamics
Expression system: Not provided

Quick links

Citations

3 review citations

Chemistry and structural biology of DNA damage and biological consequences.
Stone et al. (2011)
2 more