› 2hwv

X-ray diffraction
1.9Å resolution

Crystal structure of an essential response regulator DNA binding domain, VicRc in Enterococcus faecalis, a member of the YycF subfamily.

Released:
DOI: 10.2210/pdb2hwv/pdb
PDB entry 2hwv coloured by chain, front view.
PDB entry 2hwv coloured by chain, side view.
PDB entry 2hwv coloured by chain, top view.
Source organism: Enterococcus faecalis V583
Primary publication:
Structure of the response regulator VicR DNA-binding domain.
Trinh CH, Liu Y, Phillips SE, Phillips-Jones MK
Acta Crystallogr D Biol Crystallogr 63 266-9 (2007)
PMID: 17242520

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182821 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcriptional regulatory protein WalR Chain: A
Molecule details ›
Chain: A
Length: 121 amino acids
Theoretical weight: 14.19 KDa
Source organism: Enterococcus faecalis V583
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q836C2 (Residues: 134-234; Coverage: 43%)
Gene names: EF_1193, vicR
Sequence domains: Transcriptional regulatory protein, C terminal
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

1 bound ligand:
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P43
Unit cell:
a: 36.235Å b: 36.235Å c: 73.935Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.179 0.236
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

A matter of life and death: cell wall homeostasis and the WalKR (YycGF) essential signal transduction pathway.
Dubrac et al. (2008)
2 other articles

2 mentions without citation

Structure of the response regulator VicR DNA-binding domain.
Trinh et al. (2007)
1 more