› 2hy6

X-ray diffraction
1.25Å resolution

A seven-helix coiled coil

Released:
DOI: 10.2210/pdb2hy6/pdb
PDB entry 2hy6 coloured by chain, front view.
PDB entry 2hy6 coloured by chain, side view.
PDB entry 2hy6 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
A seven-helix coiled coil.
Liu J, Zheng Q, Deng Y, Cheng CS, Kallenbach NR, Lu M
Proc Natl Acad Sci U S A 103 15457-62 (2006)
PMID: 17030805

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
homo heptamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136534 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
General control transcription factor GCN4 Chains: A, B, C, D, E, F, G
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 34 amino acids
Theoretical weight: 3.64 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P03069 (Residues: 251-281; Coverage: 11%)
Gene names: AAS101, AAS3, ARG9, GCN4, YEL009C
Sequence domains: Basic region leucine zipper

Ligands and Environments

1 bound ligand:
Ligand HEZ 8 x HEZ
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4C
Spacegroup: P1
Unit cell:
a: 31.487Å b: 35.302Å c: 48.985Å
α: 86.54° β: 104.28° γ: 99.95°
R-values:
R R work R free
0.182 0.181 0.209
Expression system: Escherichia coli

Quick links

Citations

23 review citations

Fifty years of coiled-coils and alpha-helical bundles: a close relationship between sequence and structure.
Parry et al. (2008)
22 more

6 mentions without citation

Classification of intrinsically disordered regions and proteins.
van der Lee et al. (2014)
5 more