› 2hyn

Solution NMR

Complete ensemble of NMR structures of unphosphorylated human phospholamban pentamer

Released:
DOI: 10.2210/pdb2hyn/pdb
PDB entry 2hyn coloured by chain, ensemble of 184 models, front view.
PDB entry 2hyn coloured by chain, ensemble of 184 models, side view.
PDB entry 2hyn coloured by chain, ensemble of 184 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure determination of symmetric homo-oligomers by a complete search of symmetry configuration space, using NMR restraints and van der Waals packing.
Potluri S, Yan AK, Chou JJ, Donald BR, Bailey-Kellogg C
Proteins 65 203-19 (2006)
PMID: 16897780

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150830 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cardiac phospholamban Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 52 amino acids
Theoretical weight: 6.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P26678 (Residues: 1-52; Coverage: 100%)
Gene names: PLB, PLN
Sequence domains: Phospholamban
Structure domains: Phospholamban

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: Complete SCS search, Energy-minimization
Expression system: Escherichia coli BL21(DE3)

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Citations

18 citation in other articles

Phosphorylation and mutation of phospholamban alter physical interactions with the sarcoplasmic reticulum calcium pump.
Glaves et al. (2011)
17 more

6 mentions without citation

The role of junctophilin proteins in cellular function.
Lehnart et al. (2022)
5 more