› 2hz5

X-ray diffraction
2.1Å resolution

Crystal structure of human dynein light chain Dnlc2A

Released:
DOI: 10.2210/pdb2hz5/pdb
PDB entry 2hz5 coloured by chain, front view.
PDB entry 2hz5 coloured by chain, side view.
PDB entry 2hz5 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of human dynein light chain Dnlc2A: structural insights into the interaction with IC74.
Liu JF, Wang ZX, Wang XQ, Tang Q, An XM, Gui LL, Liang DC
Biochem Biophys Res Commun 349 1125-9 (2006)
PMID: 16970917

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192469 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dynein light chain roadblock-type 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 106 amino acids
Theoretical weight: 12.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NP97 (Residues: 1-96; Coverage: 100%)
Gene names: BITH, DNCL2A, DNLC2A, DYNLRB1, HSPC162, ROBLD1
Sequence domains: Roadblock/LC7 domain
Structure domains: Dynein light chain 2a, cytoplasmic

Ligands and Environments

1 bound ligand:
Ligand CS 1 x CS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P61
Unit cell:
a: 83.15Å b: 83.15Å c: 98.128Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.22 0.203 0.229
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Structural atlas of dynein motors at atomic resolution.
Toda et al. (2018)
4 other articles

7 mentions without citation

TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts.
Shen et al. (2009)
6 more