› 2i3b

Solution NMR

Solution Structure of a Human Cancer-Related Nucleoside Triphosphatase

Released:
DOI: 10.2210/pdb2i3b/pdb
PDB entry 2i3b coloured by chain, ensemble of 20 models, front view.
PDB entry 2i3b coloured by chain, ensemble of 20 models, side view.
PDB entry 2i3b coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR structure and functional characterization of a human cancer-related nucleoside triphosphatase.
Placzek WJ, Almeida MS, Wüthrich K
J Mol Biol 367 788-801 (2007)
PMID: 17291528

Function and Biology Details

Reaction catalysed: 
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189705 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cancer-related nucleoside-triphosphatase Chain: A
Molecule details ›
Chain: A
Length: 189 amino acids
Theoretical weight: 20.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9BSD7 (Residues: 2-190; Coverage: 100%)
Gene names: C1orf57, NTPCR
Sequence domains: NTPase
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Purinergic signalling and cancer.
Burnstock et al. (2013)
7 other articles

2 mentions without citation

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Borgio et al. (2018)
1 more