› 2icc

X-ray diffraction
1.2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195112 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
V-set and immunoglobulin domain-containing protein 4 Chain: A
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 13.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y279 (Residues: 19-137; Coverage: 31%)
Gene names: CRIg, UNQ317/PRO362, VSIG4, Z39IG
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P212121
Unit cell:
a: 30.257Å b: 50.757Å c: 61.965Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.135 0.134 0.172
Expression system: Escherichia coli

Quick links

Citations

38 review citations

Complement-targeted therapeutics.
Ricklin et al. (2007)
37 more

6 mentions without citation

Structural biology of complement receptors.
Santos-López et al. (2023)
5 more