› 2icp

X-ray diffraction
1.88Å resolution

Crystal structure of the bacterial antitoxin HigA from Escherichia coli at pH 4.0. Northeast Structural Genomics Consortium TARGET ER390.

Released:
DOI: 10.2210/pdb2icp/pdb
PDB entry 2icp coloured by chain, front view.
PDB entry 2icp coloured by chain, side view.
PDB entry 2icp coloured by chain, top view.
Source organism: Escherichia coli CFT073
Entry authors: Arbing MA, Abashidze M, Hurley JM, Zhao L, Janjua H, Cunningham K, Ma LC, Xiao R, Liu J, Baran MC, Acton TB, Rost B, Inouye M, Woychik NA, Montelione GT, Hunt JF, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-159223 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Uncharacterized HTH-type transcriptional regulator YddM Chain: A
Molecule details ›
Chain: A
Length: 94 amino acids
Theoretical weight: 10.65 KDa
Source organism: Escherichia coli CFT073
Expression system: Escherichia coli
UniProt:
  • Canonical: P67700 (Residues: 1-94; Coverage: 100%)
Gene names: c1909, yddM
Sequence domains: Helix-turn-helix
Structure domains: lambda repressor-like DNA-binding domains

Ligands and Environments

1 bound ligand:
Ligand MG 1 x MG
1 modified residue:
Ligand MSE 5 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2
Unit cell:
a: 83.127Å b: 23.526Å c: 41.593Å
α: 90° β: 94.05° γ: 90°
R-values:
R R work R free
0.184 0.184 0.225
Expression system: Escherichia coli

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