› 2iec

X-ray diffraction
2.33Å resolution

Crystal Structure of uncharacterized conserved archael protein from Methanopyrus kandleri

Released:
DOI: 10.2210/pdb2iec/pdb
PDB entry 2iec coloured by chain, front view.
PDB entry 2iec coloured by chain, side view.
PDB entry 2iec coloured by chain, top view.
Source organism: Methanopyrus kandleri
Entry authors: Bonanno JB, Ramagopal UA, Dickey M, Bain KT, Powell A, Ozyurt S, Wasserman S, Sauder JM, Burley SK, Almo SC, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed: 
7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186309 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dihydroneopterin aldolase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 131 amino acids
Theoretical weight: 14.96 KDa
Source organism: Methanopyrus kandleri
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8TX89 (Residues: 2-121; Coverage: 99%)
Gene names: MK0786, mptD
Sequence domains: Dihydroneopterin aldolase
Structure domains: 7,8-dihydroneopterin aldolase (MptD)

Ligands and Environments

1 bound ligand:
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P41212
Unit cell:
a: 60.833Å b: 60.833Å c: 263.945Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.202 0.296
Expression system: Escherichia coli BL21(DE3)

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