› 2igr

Solution NMR

Solution structure of CB1a, a novel anticancer peptide derived from natural antimicrobial peptide cecropin B

Released:
DOI: 10.2210/pdb2igr/pdb
PDB entry 2igr coloured by chain, ensemble of 20 models, front view.
PDB entry 2igr coloured by chain, ensemble of 20 models, side view.
PDB entry 2igr coloured by chain, ensemble of 20 models, top view.
Source organism: Hyalophora cecropia
Primary publication:
Structure and function of a custom anticancer peptide, CB1a.
Wu JM, Jan PS, Yu HC, Haung HY, Fang HJ, Chang YI, Cheng JW, Chen HM
Peptides 30 839-48 (2009)
PMID: 19428759

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162754 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Anticancer peptide CB1a Chain: A
Molecule details ›
Chain: A
Length: 34 amino acids
Theoretical weight: 4.2 KDa
Source organism: Hyalophora cecropia
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing
Expression system: Not provided

Quick links

Citations

10 review citations

From antimicrobial to anticancer peptides. A review.
Gaspar et al. (2013)
9 more

5 mentions without citation

Current scenario of peptide-based drugs: the key roles of cationic antitumor and antiviral peptides.
Mulder et al. (2013)
4 more